Based on the knowledge that NF-κB seems to play a crucial role in spheroid formation of MCF-7 breast cancer cells [34] and that NF-κB subunit p65 (RelA) accumulates in thyroid cancer cells on the RPM [40], we decided to target RelA in μg-grown thyroid cancer cells using DEX. The gene discussed is NFKB1; the disease is thyroid gland carcinoma.