For mesothelioma, key interactions (either positive or negative, with Spearman and/or Pearson coefficients with absolute values > 0.3) included CDK2-TXN2 (neg), CDK2-FOXM1 (pos), CDK2-CSNK2A1 (gene for CK2) (pos), CDK4-NFKB1 (neg), CDK4-FOXM1 (pos), CDK5-TXN2 (pos), CDK5-GLRX2 (pos), CDK5-NFKB1 (neg), CDK5-CSNK2B (pos), TXN-GLRX2 (pos), TXN-CSNK2B (pos), TXN2-GLRX2 (pos), TXN2-CSNK2B (pos), and HIF1-TXN2 (neg). The gene discussed is TXN2; the disease is mesothelioma.