Unexpectedly, the top 3 copy number variants for both mesothelioma and pancreatic cancer were the same: CDKN2A (encoding p16INK4a), CDKN2B (encoding p15INK4b), MTAP (encoding methylthioadenosine phosphorylase), DMRTA1 (doublesex and mab-3 related transcription factor 1), and LINC01239 (long intergenic non-protein coding RNA 1239). The gene discussed is MTAP; the disease is familial pancreatic carcinoma.