The level of MAC-1 and IL-6 in the AD group were significantly elevated (8.2- and 5.0-fold, respectively) compared with the expression in the CON group, but the MAC-1 and IL-6 level were significantly reduced (p < 0.05) after treatment with AD+CA-80 (1.5- and 3.4- fold, respectively). This evidence concerns the gene IL6 and Alzheimer disease.