Four kinases-serine/threonine-protein kinase Nek2 (NEK2), aurora kinase A (AURKA), cyclin-dependent kinase 1 and 2 (CDK1 and CDK2) were the predicted to be activated across breast cancer, colon cancer, LUAD, ovarian cancer, and UCEC (Figure 5a). This evidence concerns the gene CDK1 and malignant colon neoplasm.