[11C]Met uptake is mediated by the amino acid transporter LAT1 and has been widely used for the detection of CNS tumors, including glioma, germinoma, CNS lymphoma, CNS metastases, meningioma, mixed neural/glial tumors, and central neurocytoma [49,50,51,52,53]. The gene discussed is SLC38A7; the disease is central nervous system neoplasm.