A high transcription rate of at least some genes, which were found overexpressed in all cancer cell types according to Figure 1D, crucial for cell divisions (CDK2, CDK4, PCNA, CHEK2, CCNB) and removal of DNA damage (BRCA1 and BRCA2, XRCC1 and XRCC2, LIG1, EXO1, NEIL3—contribute to BER, NER, SSBR, MMR, and HR) [12,13], was simultaneously maintained by BRG1 and EP300 (Figure 2A,C). This evidence concerns the gene LIG1 and cancer.