Next to other intracellular infections such as HIV and HCV [27,28], this SNP was linked to TB, as the truncated version of TLR8 +1G has been found to protect against active pulmonary TB in Indonesian, Russian, and Moldavian males [29,30], in Turkish children [31], and in two Indian cohorts for both pulmonary TB (PTB) and extra-pulmonary TB (EPTB) [8,32]. The gene discussed is TLR8; the disease is pulmonary tuberculosis.