We found that treatment with rotenone not only resulted in lower numbers of surviving neurons with degenerated morphology in our preparations of mesencephalic cells (Figure 4 and Figure 5) but was also leading to an increased mRNA expression of CHOP, also known as growth arrest- and DNA damage-inducible gene 153, in N18TG2 neuroblastoma cells (Figure 6 and Figure 7). Here, DDIT3 is linked to neuroblastoma.