TP53 and neoplasm: Different levels of damage may trigger different responses; low levels of DNA damage trigger repair and cell survival, and high levels of DNA damage trigger cell death.22 p53 is a well‐established tumour suppressor and cellular gatekeeper of genome stability.23 p53 stabilization may contribute to the different expression levels of pro‐survival and pro‐apoptosis genes.24, 25 p53 has been shown to determine cell fate through promoting cell survival or apoptosis in many works, but the specific mechanism of this role remains to be revealed.