For examples, polycomb repressive complex 2 induces gene silencing through H3K27me3 in several cancers,92, 93, 94 and lysine methyltransferases SUV39H1 and Nanog regulate several oncogene expression in various cancer cells.95, 96 Recent work has provided a fact that the activation, regulation, and functions of MEKK kinases and tyrosine phosphorylation in several cancers.97, 98 Therefore, miR24‐2 may play an important role through these related genes during hepatocarcinogenesis. The gene discussed is SUV39H1; the disease is cancer.