In contrast, the gain‐of‐function phenotype caused by ECT2/Pbl overexpression is a neoplastic tumour‐like phenotype and clearly involves ectopic spreading of the apical Cdc42‐Par6‐aPKC complex, in addition to persistent cell rounding in both cuboidal follicle cells and pseudostratified wing epithelial cells (Figs EV5 and EV6). This evidence concerns the gene PARD6A and neoplasm.