Glucose transporters play a key role in the regulation of cellular glucose uptake, but their research in these two PD models has been very modest with only few studies available on this topic in mice MPTP models (Table 1); two studies reported no changes in cerebral GLUT1 level in the acute phase (Lagrue et al. 2010; Puchades et al. 2013), while a study of Sarkar et al. (2014) demonstrated decreased GLUT1 expression in the striatum accompanied by decreased expression of DAT in the caudatus/putamen and the substantia nigra regions 5 weeks following MPTP treatment. The gene discussed is SLC6A3; the disease is Parkinson disease.