According to univariate Cox analysis of factors associated with OS, the histological grade, pT stage, PD-L1 expression by tumor cells, TILD, and tumor type (based on PD-L1 expression by tumor cells and TILD) were all prognostic indicators, but only the histological grade and tumor type were significant determinants according to multivariate analysis (Table 3). The gene discussed is CD274; the disease is neoplasm.