GLP1R and diabetes mellitus: Important examples are sodium-glucose transport protein 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor (GLP1) agonists when used to treat type 2 diabetes mellitus.12,13 In some diseases where several drugs are available, a specific drug may be chosen because of its known weight-lowering side effect, for example, Topiramate seems to be a good treatment option for obese patients with migraine.