We report here that SOX11, a developmental and neuronal TF6, is overexpressed in the E/R and T/P subtypes of BCP-ALL and also in novel E/R-like, IKZF1 N159Y, MEF2D rearrangement, and DUX4 rearrangement subtypes. This evidence concerns the gene IKZF1 and acute lymphoblastic leukemia.