In the cortex of people with schizophrenia, SST mRNA reductions are typically of a larger magnitude and can be as robust (if not more robust) than the more often studied PVALB mRNA changes8,20,21,24, with widespread decreases in SST mRNA reported in dlPFC, orbital frontal cortex, anterior cingulate cortex, motor cortex, and visual cortex8,20,21,24. This evidence concerns the gene SST and schizophrenia.