UBE2T and Fanconi anemia: Both the DepMap (Fig. 7b) and STRING (Fig. 7c) networks have a cluster containing many Fanconi anemia genes that score as hits in these screens, including UBE2T, which was validated in patients as a causal gene for Fanconi anemia64, as well as TRAIP, which has recently been mechanistically connected to the pathway65.