APA factor expression is altered in a variety of cancer types and promotes tumorigenesis by regulating the expression of oncogenes (via loss of miRNA regulation) and tumor suppressors (via disruption of competing-endogenous RNA cross talk) (Masamha et al. 2014; Li et al. 2015; Chen et al. 2018b; Mitra et al. 2018; Park et al. 2018). This evidence concerns the gene ENPEP and neoplasm.