The most commonly reported medications were piperazine derivatives (R06AE) for allergy, selective beta-2-adrenoreceptor agonists (R03AC) for asthma, methyldopa (C02AB) for cardiovascular diseases, glucocorticoids (H02AB) for rheumatic diseases, fast-acting insulin (A10AB) for diabetes, other antiepileptic drugs (N03AX) for epilepsy, and aminosalicylic acid and similar agents (A07EC) for inflammatory bowel diseases. This evidence concerns the gene ADRB2 and cardiovascular disorder.