Erener et al. (2012b) reported hypercholesterolaemia in PARP1 knockout mice. The pattern of polyunsaturated fatty acid metabolites is dysregulated in PARP1 knockout mice (Kiss et al. 2015) and there seems to be a correlation between PARP1 activity and erythrocyte membrane composition (Bianchi et al. 2016). Furthermore, the composition of membrane-constituent lipids was altered upon the deletion of PARP2 (Marton et al. 2018b). The gene discussed is PARP1; the disease is Hypercholesterolemia.