A decreased level of ARG-1 expression was found in SSClowCD11b+F4/80+ and CD11b+CD11c+ cells from infected mice at 12 months compared to that at 9 months post-infection (F(3, 12) = 3.963, P = 0.002 and F(3, 12) = 26.29, P < 0.001, respectively). The gene discussed is ITGAM; the disease is infection.