Considering our previous finding that BRD7 is lowly expressed and positively correlated with prognosis in breast cancer samples [8], which is consistent with the results of Nigro et al. [7], To gain a more general insight into the association between BRD7 and YB1 in clinical specimens, we used IHC to examine the molecular expression level of YB1 in a total of 220 human breast cancer samples and 43 normal breast samples. The gene discussed is BRD7; the disease is breast carcinoma.