Importantly, combined with the results of our previous studies [8], clinical data analysis revealed that BRD7 is negatively correlated with YB1 and that low expression of BRD7 combined with high expression of YB1 is an effective marker for poor prognosis and is associated with tumor size, distant metastasis and advanced TNM stage in breast cancer patients. The gene discussed is YBX1; the disease is breast carcinoma.