UCP1 and familial hypercholesterolemia: When all participants were included, rs3811787 of UCP1 showed a protective effect to STDR (T allele, p = 0.007, OR = 0.490) (Table 6), and the association existed after the adjustment for age, gender, BMI, high blood pressure, hypercreatininemia, hypercholesterolemia, hyperlipidemia and HbA1c (T allele, p = 0.034, OR = 0.732) (Table 3).