FANCB and ovarian carcinoma: In ovarian cancer cells, the concentration needed to reach 50% of the maximum cytotoxic effect (EC50) was higher in free L-BSO than in l-BSO@PUREG4-FA2, indicating a more effective delivery of l-BSO by the l-BSO@PUREG4-FA2 nanoformulation in comparison to free l-BSO applied directly to the culture media (Figure 2 and Figure 3).