These results suggest that tumor cells swallow MSC and then acquire a dormant-senescent phenotype, characterized by cell cycle arrest; a high resistance to starvation; and, interestingly, a secretome similar to SASP that includes CSF3 (granulocyte colony-stimulating factor), PTGS2 (COX2), TNF-α, IL1-α, IL1-β, IL-6, IL-8, CXCL1, CXCL2, CXCL10 (IP10), and CCL20, as well as the antiapoptotic factor IFI6 and the tumor suppressor EGR1. This evidence concerns the gene PTGS2 and neoplasm.