FTO and metabolic syndrome: Some reports claim that the lack of association of FTO rs9939609 variant and MetS among African Americans may be due to the differences in linkage disequilibrium patterns and that this genetic effect may be captured by different markers in Whites than African Americans.[42] However, in our analysis, through interactions with BMI and physical activity, we observed higher risks that were statistically significant for AT moderate risk carriers among African Americans, but confidence intervals were wide, which demonstrated low statistical power or a chance finding.