MBNL2, TNS1 and STAB1 were all reduced in the patients with bone metastatic PCa compared with that in patients with primary PCa (GEO: http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32269 and http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE77930). Here, MBNL2 is linked to posterior cortical atrophy.