In the tissue sections from a 14-year-old AP patient with non-Hodgkin lymphoma an adult-like pattern in AMHR-2 expression could be identified (Fig. 3e); contrarywise, in the tissue sections from a 5-year-old AP patient with Hodgkin lymphoma, intense, diffuse staining was observed (Fig. 3f) suggesting a change in the expression patterns of AMHR-2 during the transition through puberty. Here, AMHR2 is linked to alkaline phosphatase measurement.