PDPK1 and cervical carcinoma: In addition, in C33A and HeLa cells, si-PDPK1 can reverse the effect of CAR10 overexpression on promoting the proliferation of cervical cancer cells (Figures 7(h)–7(j)) and upregulating the expression of cyclin A1, cyclin B1, and CDK2 (Figures 7(k) and 7(l)).