CEACAM5 and neoplasm: Third, liver metastases in the ablation group were diagnosed on the basis of CEA and contrast enhancement of CT or MRI, lacking of histopathologic evaluation of the target area, as some published reports had described that such an examination could identify important information about tumor biology and the potential risk for progression before or after treatment (Motoyoshi et al., 2010; Sofocleous et al., 2013).