TP53 and glioblastoma: Wiencke and colleagues found that secondary glioblastomas have more TP53 mutations that occur more frequently in Black and Asian patients.80 Conversely, Whites tend to harbour EGFR amplifications.66 As both secondary glioblastomas and TP53 mutations have an improved prognosis and longer survival times compared to primary glioblastoma and EGFR amplification, this may explain why Blacks and Asians with glioblastoma live longer than Whites.