Six genes out of the 13 candidates were down-regulated at the transcriptional level (C1QBP, CDKN2A, ZMYM6, BCAP31, HIST1H1D and PTMS), while four were upregulated (EIF3K, RACK1, TAPBPL and BTNL8), however, proteomic data demonstrated all their corresponding protein abundances were down-regulated, In SiHa cells, the 13 gene candidates were expressed in a corresponding pattern to the transfected HEK293 cells, suggesting that E7 drives the expression pattern of these genes candidates in same manner that HPV drives their expression in cancer. Here, H1-3 is linked to cancer.