Interestingly, these genes comprised 6 of the 7 genes that are downregulated in the control cervical cancer cell lines (SiHa and C33A): C1QBP (p = 0.0092), CDKN2A (p = 0.0008), ZMYM6 (p = 0.0006), BCAP31 (p < 0.0001), HIST1H1D (p = 0.0294), NPM3 (p = 0.0083) and PTMS (p = 0.0053) as shown in Fig. 5. This evidence concerns the gene H1-3 and cervical cancer.