Inflammatory cells infiltrate into liver was inhibited in mice compared with the control group, and MgTX (100 nM) could attenuate ALI in LPS+D-GAIN model and inhibit macrophage migration (CD68+) from peritoneal cavity to liver tissues (Fig. 1B), furthermore, special markers (CD45+, CD11b+, CCR2+, Gr1+) are used by flow cytometry to identify the CD68+ cells are infiltrating monocytes (Fig. 1C). Here, ITGAM is linked to acute respiratory distress syndrome.