Results showed higher staining of CD86 (118/157, 75%), ICOSLG (122/157, 77%), B7-H3 (138/157, 88%), B7-H7 (138/157, 88%), and B7-DC (104/157, 66%) and overall lower staining of CD80 and B7-H6 in gastric cancer tissues. This evidence concerns the gene CD276 and gastric cancer.