APOBEC3B and cancer: Analysis of donor-matched expression data further suggests that rs2142833 is a cis-expression quantitative trait locus (eQTL) for APOBEC3B at the pan-cancer level (β = 0.19, P = 2 × 10−6) (Extended Data Fig. 10g, h), consistent with cis-eQTL studies in normal cells68,69.