CDK4 and cancer: These include well-known cancer-associated genes, such as CCND1 (25 tumors), CDK4 (25 tumors), MDM2 (23 tumors), SETDB1 (23 tumors), ERBB3 (11 tumors), ERBB2 (11 tumors), MYC (10 tumors) and MYCN (five tumors).