In good agreement with the UBC13-stabilizing function of OTUB1 in TgPFN-stimulated BMDCs (Fig. 3f), we detected the increased expression of UBC13 in CD8+ cDC1s, PDCA1+ DCs, and CD11b+ cDC2s isolated from OTUB1fl/fl mice after infection with T. gondii (Fig. 4b, first top panel), confirming the critical role of OTUB1 in stabilizing UBC13 in DCs in vivo. This evidence concerns the gene OTUB1 and infection.