Regarding SSc, two independent signals were observed after conditional regression analysis, HLA-DPB1*1301 (p = 1.77 × 10−19, OR = 2.79) and HLA-DRB1*1104 (p = 1.21 × 10−12, OR = 1.83). The gene discussed is HLA-DRB1; the disease is systemic sclerosis.