This was apparent in the molecular stratification of samples by mRNA of tumor cells (log-rank PTC = 0.019, HR = 1.5) and tumor-adjacent cells (PTAC = 8.3 × 10−4, HR = 1.8) as well as gene copy number amplifications (PCNA = 9.8 × 10−4, HR = 2.8) (Fig. 3d). This evidence concerns the gene PCNA and neoplasm.