MTREX and hepatocellular carcinoma: To reveal the clinical relevance of the expression levels of MTR4 in HCC, we analyzed the correlation between the expression levels of MTR4 in the resected HCC tissues and the prognosis of corresponding HCC patients, indicating that the expression levels of MTR4 in HCC tissues are inversely correlated with the recurrence-free survival (RFS) of HCC patients (Fig. 1e, f).