Low TfR1 mRNA levels were associated with a substantial worse survival in GC patients with high CD8 mRNA levels divided by the mean of CD8 (CD8A + CD8B)/2, but not in the low CD8 mRNA group (Wilcoxon P = 0.0489 and 0.4298, respectively) (Fig. S3d). This evidence concerns the gene CD8B and gastric cancer.