To date, the secondary benign tumors including mucinous cystadenomas, compound nevus, blue nevus, prolactinoma, ACTH-producing pituitary adenoma, epithelioid hemangioma, sebaceous adenoma and benign skin adnexal tumor arising in mature cystic teratomas of the ovary have been described [3]. The gene discussed is POMC; the disease is epithelioid hemangioma.