SERPINE1 and urinary bladder neoplasm: At week 20, 2 of 10 bladder tumors demonstrated NMIBC and 8 of 10 bladder tumors demonstrated MIBC in WT mice, while 5 of 11 bladder tumors demonstrate NMIBC and 6 of 11 bladder tumors demonstrate MIBC in PAI-1 KO mice.