CF inhibited the mRNA expression of NFATc1 (P < 0.01) and c-Fos (P < 0.05) (Fig. 4A and a) and the proteins expression levels of the corresponding NFATc-1 (P < 0.01) and c-Fos (P < 0.01) were decreased by CF (Fig. 4B and b). Here, FOS is linked to cystic fibrosis.