CMA1 and congestive heart failure: Results showed the effects of QLQX in multiple mechanism pathways in treating CHF, such as by regulating the balance of proinflammatory and anti-inflammatory cytokines [20], down-regulating the cardiac chymase signaling pathway and chymase-mediated angiotensin II production [21], inhibiting the myocardial inflammation and cardiomyocyte death to promoted cardiomyocyte proliferation [22].