In line with this, the N-terminal human sequence 1–14 (hNGF1–14) and its acetylated derivative Ac-hNGF1–14 demonstrated a good NGF-like in vitro activity by protecting PC12 cells from NGF withdrawal driven degeneration [27] as well as neurotrophic signalling in PC12 and neuroblastoma cell lines [27,36]. The gene discussed is NGF; the disease is neuroblastoma.