In particular, it has been reported that increasing GSH levels by administration of N-acetyl-cysteine (NAC), a GSH precursor that has been used in therapeutic practices [155], leads to a downregulation of the proinflammatory vascular cell adhesion protein 1 (VCAM-1), a pathogenic factor in atherosclerosis, and prevents vascular damage in patients with diabetes [156]. This evidence concerns the gene VCAM1 and atherosclerosis.