Subjects with Vitamin D deficiency have significantly high values (p < 0.05) for BMI z-score, waist circumference, waist z-score, body fat percentage, FMI, systolic and diastolic BP, total cholesterol, triglycerides, LDL-C, insulin, HOMA-IR, leptin, and PTH. The gene discussed is LEP; the disease is vitamin D deficiency.