In parallel, we tested the effects of the anti-EGFR CL4 aptamer [33] on these tumor cells and, according to our previous findings [39], we observed a significant inhibition of tumor cell growth when used at the dose of 200 nM for 72 h, whereas no effect was observed with a scrambled aptamer (CL4Sc) used as a negative control. This evidence concerns the gene EGFR and neoplasm.