As shown in Figure 6 and Figure 7, the immunoconjugate induced the death of tumor cells in a dose-dependent fashion and more efficiently than both the parental moieties, by significantly increasing the secretion of IL-2 and IFNγ cytokines by both hPBMCs and NK populations, thus leading to increased cell lysis with a higher lactate dehydrogenase (LDH) release by tumor cells. The gene discussed is IFNG; the disease is neoplasm.