EIF4G1 and poliovirus infection: While we demonstrated that the eukaryotic initiation factor eIF4G is cleaved in both WT and KO TDP2 hRPE-1 cells during poliovirus infection, indicating that host cap-dependent translation is shut-off by the virus, host translation continues to occur throughout CVB3 infection of MEFs (Ullmer and Semler, unpublished observation).